Research Comparison
Selank vs Semax
An educational comparison of two distinct synthetic heptapeptides, with emphasis on peptide origin, structure and experimental signalling context.
Selank
Tuftsin-derived synthetic peptide
Selank is a synthetic heptapeptide based on the tetrapeptide tuftsin, extended with a Pro-Gly-Pro sequence. Laboratory studies examine it as a distinct research compound in experimental signalling, gene-expression and peptide-interaction models.
Semax
ACTH-fragment-derived synthetic peptide
Semax is a synthetic heptapeptide derived from the amino-acid sequence of the ACTH(4–7) fragment and extended with Pro-Gly-Pro. It is examined independently in experimental signalling and gene-expression research.
Comparison table
Research classification
- Selank
- Synthetic tuftsin-derived heptapeptide used as a discrete laboratory research compound.
- Semax
- Synthetic ACTH-fragment-derived heptapeptide used as a discrete laboratory research compound.
Peptide origin
- Selank
- Based on tuftsin with a Pro-Gly-Pro extension.
- Semax
- Based on the ACTH(4–7) sequence with a Pro-Gly-Pro extension.
Peptide structure/type
- Selank
- Linear seven-amino-acid peptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro.
- Semax
- Linear seven-amino-acid peptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro.
Experimental signalling context
- Selank
- Studied in assay systems involving peptide interactions, gene expression and other model-specific signalling observations.
- Semax
- Studied in assay systems involving peptide signalling, gene expression and other model-specific molecular observations.
Interchangeability
- Selank
- Its tuftsin-derived sequence and experimental identity are specific to Selank.
- Semax
- Its ACTH-fragment-derived sequence and experimental identity are specific to Semax.
| Comparison point | Selank | Semax |
|---|
| Research classification | Synthetic tuftsin-derived heptapeptide used as a discrete laboratory research compound. | Synthetic ACTH-fragment-derived heptapeptide used as a discrete laboratory research compound. |
|---|
| Peptide origin | Based on tuftsin with a Pro-Gly-Pro extension. | Based on the ACTH(4–7) sequence with a Pro-Gly-Pro extension. |
|---|
| Peptide structure/type | Linear seven-amino-acid peptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. | Linear seven-amino-acid peptide with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. |
|---|
| Experimental signalling context | Studied in assay systems involving peptide interactions, gene expression and other model-specific signalling observations. | Studied in assay systems involving peptide signalling, gene expression and other model-specific molecular observations. |
|---|
| Interchangeability | Its tuftsin-derived sequence and experimental identity are specific to Selank. | Its ACTH-fragment-derived sequence and experimental identity are specific to Semax. |
|---|
Experimental research context
Both peptides appear in laboratory studies that measure molecular signalling and gene-expression responses. Experimental system, assay conditions, concentration range and measured endpoint must be considered when interpreting any observation.
Why they are not interchangeable
Sharing the same peptide length and a Pro-Gly-Pro segment does not make these compounds equivalent. Their first four amino acids, peptide origins and experimental identities differ, so observations involving one should not be attributed to the other.
Related research information
Review each compound separately or return to the broader educational catalogue.
For research purposes only. This page is an educational laboratory reference. It does not provide dosing, administration, medical, therapeutic, cognitive-enhancement or human-use guidance.